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Precision Medicine

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Article list Precision Medicine

  • abstractImage
    Portrait — Onur Boyman

    Researcher, Founder, Helper

    Onur Boyman became a doctor because he wanted to help people. Now, having achieved a breakthrough with his research on autoimmune diseases, the UZH professor plans to bring a new therapy to market – and switch role from head of clinic to entrepreneur.
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    Genome editing

    Use of Genetic Scissors Carries Risks

    The CRISPR tool is capable of repairing the genetic defect responsible for the immune disease chronic granulomatous disease. However, researchers at the University of Zurich have now shown that there is a risk of inadvertently introducing other defects.
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    Tumor biology

    Key Driver for Epithelial Cancer Development Identified

    A distinct signaling pathway called TNF-α drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF-α program and become invasive - they spread into other organs.
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    Regenerative Medicine

    Tailor-Made Cells

    In a few years, we’re likely to see personalized stem cells being used in the first clinical trials for heart patients. But there are still a few hurdles to overcome on the way from the lab to the clinic.
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    Cancer medicine

    Novel Blood Test Helps Improve Cancer Treatments

    UZH and USZ researchers have further developed a new blood test to analyze liquid biopsies of DNA fragments in the blood. The new method is fast and practical, without putting much of a strain on patients – and might help to treat cancer patients more individually in the future.
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    Stem cell biology

    The Mechanism Behind Melanoma Resistance to Treatment

    In many cases of malignant melanoma, the effect of targeted treatment is lost over time. A research team from UZH and USZ has now discovered that a factor secreted by tumor cells is responsible for the resistance.
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    Gender medicine

    Strong Hearts

    The heart is our most vital organ. But the heart muscle cells are sluggish. The cardiologist Carolin Lerchenmüller is exploring how these cells are regenerated and how the heart can be strengthened and protected.
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    Permanent professorship

    UZH to Create Chair of Allergology and Asthma in Davos

    The Swiss Institute of Allergy and Asthma Research (SIAF) in Davos is to be significantly strengthened with the creation of a Chair of Allergology and Asthma. An agreement on this was announced on 21 June 2024 by representatives of the Graubünden government and the UZH.
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    Gender medicine

    The Thing with Mice

    For many years, the male mouse was thought to be the measure of all things in pre-clinical research. Over time, scientists have come to realize that it is medically necessary to work with experimental animals of both sexes.
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    Gender medicine

    Protective Genes

    Men are more likely to develop and die of cancer, and most types of cancer affect more men than women. This is not only down to genes, but also behavior.
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    Precision Medicine

    Fighting Cancer with SMARTdrugs

    With “SMARTdrugs” a team of researchers from UZH with international partners aims to create a new class of therapies: “radiotheranostics”. These drugs combine diagnostic and therapeutic radionuclides in a supramolecular compound with the purpose of imaging and treating tumors.
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    Gender Medicine

    The Right Medicine for Women and Men

    Many illnesses have sex- and gender-specific causes and symptoms, many of which have received little research attention thus far. That, however, is about to change. UZH has established the first professorial chair in gender medicine in Switzerland to advance research in this field.
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    New UZH Magazin

    Healthy Women, Healthy Men

    Many diseases manifest differently in women and men. The symptoms for heart disease, stroke, depression and cancer can look very different depending on your sex. Researchers in the field of gender medicine are looking into these gender-specific differences and developing the right therapies. The new UZH Magazin shines a light on the significance of this field.
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    INTeRCePT Research Project

    Better Prognosis for Blood Cancers

    Being handed a diagnosis of cancer often turns people’s lives upside down. When the cancer is blood cancer, the impact is even more dramatic. Although the chances of recovery have improved greatly in recent years, recurrences are still relatively common. A research team led by Thorsten Zenz is working on reducing the risk of relapse.
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    mTORUS

    Helpful Viruses

    Researchers at UZH and ETH Zurich have rediscovered a long-neglected treatment for urinary tract infections – bacteriophages. These viruses can be used to fight bacterial infections without the side effects caused by antibiotics. However, approval is still a long way off.
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    Biomedical Technology

    Visualizing Multiple Sclerosis with a New MRI Procedure

    The loss of myelin sheaths in the brain is a hallmark of multiple sclerosis. Researchers at ETH Zurich and the University of Zurich have now developed an MRI method that maps the condition of this nerve insulation layer more accurately than before.
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    The LOOP Zurich – Annual Event

    Data for the Medicine of the Future

    Medical research requires enormous amounts of data to achieve the breakthroughs that make a difference. The more the better – high computing capacities and large amounts of data can aid the development of new diagnoses and treatment methods. The LOOP Zurich is a pioneer in this area, as the center’s annual event showcased.
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